Immunoregulatory Properties of Arteether in Folic Acid-Chitosan-Fe3O4 Composite Nanoparticle in 4T1 Cell Line and Mice Bearing Breast Cancer
نویسندگان
چکیده
منابع مشابه
Anti-cancer and anti-immunomodulatory properties of novel Arteether in Folic acid-Chitosan-Fe3O4 composite nanoparticle for treatment of breast cancer
Goal: The potent anti-cancer activity of Arteether (ARE) has been the focus of many studies. However, the hydrophobic property of this drug limits its application. To increase the bioavailability of ARE, we formulated a nanosystem (NS) of folic acid (FA), chitosan (CS) and Fe3O4 for delivery of ARE against breast cancer. Material and Methods: The CS coated Fe3O4 was synthesized by co-precipitat...
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Background: Chemo-immunotherapy is one of the new achievements for treatment of cancer, by which the success of anti-cancer therapy can be increased. In vitro studies have been shown that Arteether (ARE) induces apoptosis in tumor cells, but not in normal cells. Objective: To investigate the cytotoxic and immunomodulatory properties of Arteether in-vivo and in-vitro. Methods: In this study, we ...
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متن کاملarteether exerts antitumor activity and reduces cd4+cd25+foxp3+ t-reg cells in vivo
background: chemo-immunotherapy is one of the new achievements for treatment of cancer, by which the success of anti-cancer therapy can be increased. in vitro studies have been shown that arteether (are) induces apoptosis in tumor cells, but not in normal cells. objective: to investigate the cytotoxic and immunomodulatory properties of arteether in-vivo and in-vitro. methods: in this study, we ...
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ژورنال
عنوان ژورنال: Immunoregulation
سال: 2019
ISSN: 2588-5200,2588-6088
DOI: 10.32598/immunoregulation.1.4.207